The Purdue Libraries, Archives and Special Collections Psychoactive Substances Research Collection was established in 2006 with a generous gift from the Betsy Gordon Foundation. This cohesive collection seeks to document the international history of psychoactive substances and their benefits to medicine and healing, as well as to perpetuate the legacy of each past, present, and future scientist's contributions to this area of research. Currently, no comprehensive collection of archival material on psychoactive substances research exists, therefore it is imperative to create a central repository where such primary source materials can be archived and made accessible to future researchers.

The Purdue University Libraries Archives and Special Collections actively collects primary source materials relating to the scientific research, medical, and therapeutic use of substances that facilitate non-ordinary states of consciousness.